How much thicker is the left ventricle compared to the right ventricle?

The left ventricle is indeed thicker than the right ventricle, and this difference is primarily due to the functional demands placed on each chamber of the heart. The left ventricle is responsible for pumping oxygenated blood throughout the entire body, which requires it to generate a higher pressure than the right ventricle, which only pumps blood to the lungs for oxygenation.

As a result, the muscular walls of the left ventricle are significantly thicker, allowing it to withstand and generate the higher pressures necessary for systemic circulation. Typically, the left ventricle's wall can be two to three times thicker than that of the right ventricle. This anatomical difference is critical for the efficient functioning of the circulatory system, ensuring that blood is effectively delivered to all body tissues.